Equal parts brilliant and controversial, scientist Moira O'Deorain is on the cutting edge of genetic engineering, searching for a way to rewrite the fundamental building blocks of life.
Over a decade ago, O'Deorain made waves when she published a controversial paper detailing a methodology for creating custom genetic programs that could alter DNA at a cellular level. It seemed like a promising step toward overcoming diseases and disorders and maximizing human potential.
Dissent among her peers soon followed. Many considered her work to be dangerous because of its perceived ethical shortfalls, and O'Deorain was even accused of having the same unchecked desire for scientific advancement that some believed had caused the Omnic Crisis. In addition, other geneticists were unable to reproduce the results of Moira's research, which further called her discoveries into question. Instead of kickstarting her career, her paper seriously damaged her reputation.
She received a lifeline in an offer from an unlikely source: Overwatch's covert ops division, Blackwatch. She continued her work in the shadows while developing new weapons and technologies for the organization. Her employment was a closely kept secret, until it was uncovered during inquiries following the Venice incident. Many high-ranking Overwatch officials disavowed all knowledge of her affiliation with them.
After Overwatch was disbanded, O'Deorain was forced to turn to unconventional sources of funding. This time, she was invited to join the scientific collective that had founded the city of Oasis. Yet some have whispered that the shadowy Talon organization had already been supporting her for years, aiding her experiments in exchange for utilizing the results for their own purposes.
Though O'Deorain will go to any lengths to make scientific breakthroughs, her work is still unknown to most of the world. But now that she has been freed from all constraints, it is only a matter of time before everything changes.
Biotic Grasp ∞ rounds per clip Primary fire: Regeneration Piercing projectile beam type 80 healing per second 16.67 healing per second (residual) +2.4 or +10 energy per second 30 m/s projectile speed 15 m range 0.3 seconds cast time Lasts up to 9 seconds Lasts 3 seconds (residue) ✘ Cannot headshot Secondary fire: Decay Enemy-targeting beam type 50 damage per second 33 healing per second on self 20 m range ✘ Cannot headshot Using her left hand, Moira expends biotic energy to heal allies in front of her. Her right hand fires a long-range beam weapon that saps enemies’ health, healing Moira and replenishing her biotic energy. Primary Fire Key: (, , ) Secondary Fire Key: (, , )
Fade Non-damaging and self-buff movement type 18.75 m/s movement speed Lasts 0.8 seconds 6-second cooldown Disappear, move faster, and become invulnerable, but you cannot shoot. Default Key: (, , )
Biotic Orb Area-of-effect linear projectile type 50 damage per second Max 200 damage 75 healing per second Max 300 healing 16 (5.5) m/s projectile speed 10-second cooldown Moira launches a rebounding biotic sphere; she can choose between a regeneration effect that heals the allies it passes through, or a decay effect that deals damage to enemies. Default Key: (,, )
Ultimate Ability: Coalescence Channeled ultimate type Linear piercing beam ability type 70 damage per second 30 m range 140 healing per second 50 healing per second on self 9 m/s movement speed 0.5 sec cast Lasts 8 seconds ✘ Cannot headshot
Moira channels a long-range beam that both heals allies and bypasses barriers to damage her enemies. While channeling this ability, Moira's movement speed increases greatly, but she cannot perform any other actions.
Default Key: (, , )
"Surrender to my will!"
Besides these abilities, Moira is able to jump, crouch, and perform Quick Melee. Moira does not need to reload, however, her Primary Fire uses a resource system that must be replenished by either dealing damage by her Secondary Fire or waiting for it to recharge naturally.
All seasonal event items, which are marked with special event icons ( • • • • • ), are only available to be unlocked either through their respective Loot Boxes or by Credits within the event's duration.During the event, newly-introduced event items cost three times as much as non-event items of the same rarity, while returning seasonal items are unlocked at the regular price.
Like many of the other scientists represented in the game, Moira has an outward passion for science and the advancement thereof; however, unlike Mei and Winston, who are both bright-eyed individuals with altruistic motives for their respective researches, and unlike Mercy, who puts the lives and feelings of others before her, Moira doesn't have much in the way of limitations when it comes to how far she'll go in her experiments. She's tested on animals, she's tested on herself, and it was only through the involvement of Blackwatch - and later Oasis and Talon - that she was able to continue her research unimpeded.
In game, Moira gives an air of superiority, especially in her voice lines ("Stupidity is not a right."; "Injured again?"; "Unsightly.") She also doesn't show much in the way of emotion, preferring to act in a state of constant disdain at her surroundings; she will, however, take sadistic pleasure in siphoning the life force of her enemies. Perhaps somewhat oddly for a villain in Overwatch, she seems to take either a neutral or positive stance towards Omnics (though this sentiment is shared by fellow Talon member Doomfist to an extent), as she reflects upon London's "medieval" attitudes towards them when she first spawns in King's Row occasionally.
Jeff Kaplan describes her as "weirdly self-obsessed more than anything" and has a thirst and hunger for knowledge and she doesn't really care about the outcomes of her scientific decisions. He also jokingly described her as "chaotic neutral" which originates from D&D Alignment.
When 1v1ing a hero, deciding which orb to deploy is important. Use Heal orb to survive against Tanks or hard to hit targets, as she can't heal herself otherwise. Use Damage orb for engaging in long-range fights that her beam can't hit, or for finishing off a low health foe.
Let your team know when your healing meter is low. She should not be reliable as a solo healer unless you play her really safe.
Unlike Ana's healing, Moira's primary fire healing beam does not stop when it hits an ally! In a tight corridor, you can hit multiple teammates all at once.
Her Ultimate should only be used with team support. Throwing out a Healing orb will keep you sustained during it. Moving from side to side of the payload is important for hitting many targets.
Moira’s secondary attack can allow her to sustain in 1v1’s against heroes who apply damage slowly over time like Winston, Mei, or Symmetra.
Her secondary attack has a surprising range, despite the beam appearing to be very short. The beam has the same range has Roadhog’s Chain Hook, meaning you can safely approach enemies from a moderate distance.
Moira's damage orb can pass through Reinhardt and Orisa's shields, making it an excellent way of discommoding teams hiding behind a shield.
Though it can pass through keep in mind that it does not deal damage through the shield, only when it has passed the obstruction.
Because Moira's orbs bounce, throwing them into enclosed areas can make them hard to dodge or have them affect multiple targets enclosed. In circular areas, aiming carefully can have the orb continuously circulate until it runs out. In areas with low ceilings, throwing the orb straight down or upwards is the best way to maximize its use in a specific location as it will just bounce up and down, making it's healing/harming effect practically stationary.
Moira's Fade is similar to a culmination of Reaper's Wraith form and Tracer's Recall. It allows her to move rapidly for a short time as Blink does but she can determine her path like a Wraithing Reaper and she is impervious to damage like both examples. It is her best option to escape from a fight, while also being her only reliable option. Although the player sees themselves moving, to the enemy's point of view, it looks like Moira disappeared. Just as Recall does, Fade allows Moira to avoid quick ultimates if timed correctly such as D.va's Self Destruct, Junkrat's Rip-Tire, and McCree's Deadeye.
Despite its speed, Fade does not lock the direction Moira is going, players with enough practice and timing can actually create curved paths to teleport into more specific points such as behind walls or ending facing a different direction.
Despite an early bug preventing it, Moira can fade through enemies and allies.
Moira's damage orb carries a fixed amount of 200 damage, just enough to kill most heroes in the DPS and Healer category. When an ally is in the path of a biotic orb and unable to dodge, it is recommended for the rest of the team to "share" the orb and mitigate the damage.
Moira was first teased in the comic Masquerade, but it was unknown to anyone it was her. She was officially revealed on November 3, at BlizzCon 2017, then added to the PTR on November 6, 2017.
She is the first Overwatch character to have Heterochromia iridum, the condition of having 2 differently colored eyes. (In her case, her left eye is blue and her right eye is red/brown.) As can be seen in her 'Foundation' spray from the Archives 2018 event, she was born with the condition.
She is the second hero to be added to the game that can melee with both of her hands at random. The first is D.Va.
Confirmed that she is Chaotic Neutral on the DnD alignment board.
It is possible that her design was based on Moira Thaurissan, a priest in World of Warcraft.
Moira's golden weapon design, upon release, was just her cuffs. It was not until later for her to also have golden nails with her gold weapon design.
Moira's nails will not be gold with a golden weapon equipped if the player also has a team skin equipped.
Moira's team skins usually have one color on the top of her long nails and another color on the bottom.
Moira's name may be a reference to the Greek mythological "Moirai" (more often known as the Fates), white-robed incarnations of destiny that dictated the course and events of each and every mortal's lifespan. This could be reflective of Moira's desire to change and chart the evolutionary path of mankind.
Moira's name is most likely an Anglicisation of the Irish name Máire and her last name could be Anglicised as O'Dorian, perhaps a reference to the fictional immortal Dorian Grey.
Her name might also come from Doctor Moreau, from the novel by H. G. Wells, the island of Doctor Moreau, where the said character is a mad scientist and the novel deals with a number of philosophical themes, including pain and cruelty, moral responsibility, human identity, and human interference with nature.
Michael Chu confirmed that the development team referenced anime in her sprays.
The game developers also wanted her to be instantly recognizable when fans see her on the field as her running animation is similar to the popular anime character Naruto. 
Her face appearance, the red hair, the heterochromia and her Glam skin could be based on David Bowie, while the patch on her left eye could be a reference to the Phantom of the Opera.
(Confirmation needed) Her kit and bio could also be based on Kala Kapur from the universe of Evolve: both share the same occupation of geneticists and scientists who experimented on themselves for the sake of becoming stronger.
Both are able to fire a long-range beam that saps either the health of the enemies, either the armor of the monsters. They can also throw orbs to damage enemies and teleport with the exception of Kala having to place two teleporters to make them functional.